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Ann Von Holle
Education
University of North Carolina, Chapel Hill
Ph.D. in Epidemiology
Chapel Hill, NC
2018 - 2013
Thesis: Infant growth trajectories and lipid levels in adolescence
University of Pennsylvania
M.A. in Demography
Philadelphia, PA
2005
University of North Carolina, Chapel Hill
M.S. in Biostatistics
Chapel Hill, NC
2003
Johns Hopkins University
M.H.S. in Population Dynamics
Baltimore, MD
1995
University of California, San Diego
B.A. in Applied Math
San Diego, CA
1993
Research Experience
National Institute of Environmental Health Sciences
Postdoctoral Fellow, Advisor: Clarice R. Weinberg
Research Triangle Park, NC
2018 - present
- Research topics: Familial risk and biomarkers associated with breast cancer incidence
- Investigating the role of serum iron biomarkers in breast cancer incidence
- Applied survival analysis and data visualization to develop new method to estimate familial aggregation of breast cancer age of onset
- Developed analysis plans to synthesize a priori approach to projects
University of North Carolina, Department of Epidemiology
Graduate Researcher, Advisor: Kari E. North
Chapel Hill, NC
2013 - 2018
- Research topics: Infant anthropometric growth as 1) a factor associated with sociodemographic risk factors, 2) an exposure hypothesized to modify lipid levels in adolescence and 3) an effect modifier of the association between genetic risk variants and lipid levels.
- Estimated different patterns of infant growth and their association with lipid levels in adolescence with structural equation models, factor analysis, and non-linear random effects models.
- Documented all work with reproducible reports written in R, markdown and LaTeX; tracked script development with Git.
University of North Carolina, Center of Excellence for Eating Disorders (CEED)
Biostatistician
Chapel Hill, NC
2005 - 2013
- Collaborated in the planning and interpretation of statistical analyses for research papers authored by faculty, post-doctoral fellows, graduate students and undergraduate students.
- Analyzed data with regression and structural equation models in SAS and R.
- Participated in manuscript writing process, which included the statistical methods sections, data visualizations and overall data integrity.
Maryland Healthcare Commission
Research analyst
Baltimore, MD
1999 - 2000
- Assisted in the planning and production of analyses regarding the status of the uninsured in Maryland with federal survey data.
Peace Corps
Public Health Specialist
Togo, Africa
1997 - 1998
Fellowships and Awards
Individual Predoctoral Fellowship Award (Award: 16PRE29200008)
American Heart Association
N/A
2016-2018
Summer travel scholarship award
Summer Institute in Statistical Genetics
Seattle, WA
2014-2016
Ruth L. Kirschstein Pre-Doctoral Institutional National Research Service Award
National Institute of Child Health and Development, National Institutes of Health
N/A
2001-2005
Publications
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I have co-authored more than 50 peer-reviewed publications, with 2,597 citations and an H-index of 28, according to Google Scholar.
Publications available at https://orcid.org/0000-0002-0299-1114
Presentations
Oral presentations
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- Von Holle A, North KE, Gahagan S, Blanco, E, et al. Infant Growth Trajectories and Lipid Levels in Adolescence: Evidence from a Chilean Infancy Cohort. Oral presentation at American Heart Association EPI/Lifestyle; 2018; New Orleans, Louisiana.
- Von Holle A, Thornton L, Kaye W, Bulik C. Conditional Probability and Rate of Remission of Eating Disorders. Oral presentation at: International Conference of Eating Disorders; 2007; Baltimore, Maryland.
- Von Holle A Associations between Partner-Based Childcare and Fertility of Married Working Mothers. Refereed roundtable presentation at: Annual meeting of the American Sociological Association; 2006; Montreal, Canada.
- Von Holle A, Suchindran C. Data depth and infant mortality differentials. Oral presentation at: Eastern North American Region of the International Biometric Society (ENAR); 2003; Tampa, Florida.
Poster presentations
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- Von Holle A, O’Brien K, Sandler DP, Janicek R., Weinberg CR. Association Between Serum Iron Biomarkers and Breast Cancer. Poster presented at the Society of Epidemiological Research annual meeting; 2020; Virtual.
- Von Holle A, O’Brien K, Sandler DP, Weinberg CR. Familial aggregation of age of onset for breast cancer risk. Poster presented at the Society of Epidemiological Research annual meeting; 2019; Minneapolis, MD.
- Von Holle A, North KE, Gahagan S, Blanco E, et al. Sociodemographic predictors of early postnatal growth. Poster presented at the Society of Epidemiological Research annual meeting; 2018; Baltimore, MD.
- Von Holle A, North KE, Gahagan S, Blanco E, et al. Infant Growth As An Effect Modifier Of Genetic-Lipid Associations: Evidence From A Chilean Infancy Cohort. Poster presented at the American Heart Association EPI/Lifestyle annual meeting; 2018; New Orleans, Louisiana.
- Von Holle A, North KE. Confirmatory factor analysis (CFA) of multivariate lipid distributions across time and race-ethnic groups: United States, 2003-2012. Poster presented at the American Heart Association EPI/Lifestyle annual meeting; 2017; Portland, Oregon.
- Von Holle A, Justice, A, North KE, et al. Lipid-related Genetic Variants and Lipid Outcomes in a Cohort of Chilean Children. Poster presented at the American Heart Association EPI/Lifestyle annual meeting; 2017; Portland, Oregon.
- Von Holle A, North KE, Gahagan S, Tao R. The utility of standardized or crude weight measures in modeling of postnatal growth trajectories: Are there differences? Poster presented at the 2016 Epidemiology Congress of the Americas, Miami, Florida.
- Von Holle A, North KE, Kang E, Blanco E, Gahagan S. Childhood BMI Associated with Low HDL-C Levels in Adolescence in a Chilean Cohort. Poster presented at the American Heart Association EPI/Lifestyle annual meeting; 2015; Baltimore, Maryland.
- Von Holle A, U.S. Women’s Labor Force Participation, Children and Change: 1980-2000. Poster presented at the Population Association of America annual meeting; 2005; Philadelphia, Pennsylvania.
- Von Holle A, Suchindran C. A Non-Parametric Application for Exploratory Multivariate Data Analysis Using Infant Mortality Rates. Poster presented at the Population Association of America annual meeting; 2004; Boston, Massachusetts.
Teaching experience
National Institute of Environmental Health Sciences
Postdoctoral activities
Research Triangle Park, NC
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- Planned and co-lead the “Mentoring of Junior Faculties and Fellows” 1-hour session for branch retreat (October 2019)
- Guest lecturer for 2-hour short course, “Introduction to Statistics and Experimental Design” (January 2020)
As a guest lecturer, I adapted course content into a R Markdown version. Github code repository access available upon request.
University of North Carolina, Chapel Hill
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Chapel Hill, NC
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- Teaching Assistant, Advanced Epidemiologic Methods (Spring 2016)
- Guest lecturer, CEED postdoctoral yearly seminar series: “Statistical Analysis Plans in Research” (2008-2012)
As a teaching assistant, I created a github code repository for class materials: https://github.com/UNC-EPID-722/2016 and created R versions of class SAS scripts.
Professional development training
National Institute of Environmental Health Sciences
Postdoctoral training
Research Triangle Park, NC
2018 - 2019
- ‘Writing from the Reader’s Perspective’ 1-day workshop (November 2018)
- ‘Write Winning NIH Grant Proposals’ 1-day workshop (February 2019)
- ‘Scientists Teaching Science’, a 9-week pedagogy course (Spring 2019)
- Research Mentor Training (May 2019)
Professional Associations
Society of Epidemiologic Research
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2013-2021
American Heart Association
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2015-2021
American Associaton for Cancer Research
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2020-2021